Table 1

Quality assessment of studies according to the definition of pulmonary arterial hypertension and the exclusion of other forms of pulmonary hypertension

Definition of PAHPulmonary fibrosis and left heart disease excludedPulmonary fibrosis and left heart disease not excluded
RHC
 mPAP >25 mm Hg at rest and/or mPAP >30 mm Hg at exerciseA1A2
Doppler echo
 PASP/TG ≥45 mm HgB1B2
Doppler echo
 35 mm Hg ≤PASP/TG <45 mm HgC1C2
Other (or not defined)D1D2
  • For detailed definition of quality criteria A–D and category 1/2, please refer to the Methods section and the online supplement. Only if A1 studies were available, specific OMERACT criteria of 6MWT were considered validated (V) or not valid (NV) (see legend to table 2 for detailed definitions).

  • 6MWT, 6 min walk test; mPAP, mean pulmonary artery pressure; PAH, pulmonary arterial hypertension; PASP/TG, pulmonary arterial systolic pressure/tricuspid gradient; RHC, right heart catheterisation.