Table 1

Adjusted rates and rate ratios of joint surgery among patients with rheumatoid arthritis from 1983 to 2007*

1983–19871988–19921993–19971998–20022003–2007
Total
Total knee arthroplasty
Total number35294083478844725183
Adjusted rate (95% CI)478.3 (461.5 to 495.0)486.9 (471.6 to 502.1)524.1 (509.2 to 539.0)444.3 (431.3 to 457.3)460.4 (447.8 to 473.0)
Adjusted rate ratio (95% CI)1.00 (reference)1.02 (0.98 to 1.07)1.09 (1.04 to 1.14)0.92 (0.88 to 0.96)0.96 (0.92 to 1.01)
p Value0.36<0.00010.00040.10
Total hip arthroplasty
Total number23243171382536583551
Adjusted rate (95% CI)311.6 (298.2 to 325.0)377.3 (363.9 to 390.7)417.4 (404.1 to 430.6)363.4 (351.7 to 375.2)323.5 (312.8 to 334.2)
Adjusted rate ratio (95% CI)1.00 (reference)1.21 (1.14 to 1.27)1.32 (1.26 to 1.39)1.15 (1.09 to 1.21)1.02 (0.97 to 1.08)
p Value<0.0001<0.0001<0.00010.39
Total ankle arthroplasty/ankle arthrodesis
Total number296401439329269
Adjusted rate (95% CI)39.8 (35.0 to 44.5)47.2 (42.5 to 52.0)48.2 (43.7 to 52.7)32.7 (29.2 to 36.2)23.7 (20.8 to 26.5)
Adjusted rate ratio (95% CI)1.00 (reference)1.21 (1.04 to 1.40)1.21 (1.05 to 1.41)0.82 (0.70 to 0.96)0.61 (0.52 to 0.72)
p Value0.020.010.02<0.0001
Total wrist arthroplasty/wrist arthrodesis
Total number591301188335
Adjusted rate (95% CI)7.8 (5.7 to 9.8)15.1 (12.5 to 17.8)12.8 (10.5 to 15.1)8.2 (6.5 to 10.0)3.1 (2.0 to 4.1)
Adjusted rate ratio (95% CI)1.00 (reference)1.98 (1.45 to 2.69)1.66 (1.21 to 2.27)1.07 (0.76 to 1.49)0.41 (0.27 to 0.63)
p Value<0.00010.0020.71<0.0001
Age 40–59 years
Total knee arthroplasty
Total number10061149141013331562
Adjusted rate (95% CI)381.6 (357.4 to 405.7)366.6 (345.2 to 387.9)381.2 (361.3 to 401.1)301.9 (285.7 to 318.1)309.3 (293.9 to 324.8)
Adjusted rate ratio (95% CI)1.00 (reference)0.96 (0.88 to 1.05)0.99 (0.91 to 1.07)0.78 (0.72 to 0.85)0.81 (0.74 to 0.87)
p Value0.380.78<0.0001<0.0001
Total hip arthroplasty
Total number756868988987874
Adjusted rate (95% CI)286.4 (265.5 to 307.4)276.9 (258.3 to 295.5)268.1 (251.4 to 284.8)223.6 (209.6 to 237.5)172.0 (160.5 to 183.4)
Adjusted rate ratio (95% CI)1.00 (reference)0.97 (0.88 to 1.07)0.92 (0.84 to 1.01)0.77 (0.70 to 0.85)0.60 (0.54 to 0.66)
p Value0.500.09<0.0001<0.0001
Total ankle arthroplasty/ankle arthrodesis
Total number145181197146104
Adjusted rate (95% CI)52.3 (43.6 to 61.0)56.9 (48.5 to 65.3)52.5 (45.2 to 59.9)33.1 (27.7 to 38.4)20.8 (16.8 to 24.8)
Adjusted rate ratio (95% CI)1.00 (reference)1.06 (0.85 to 1.32)0.98 (0.79 to 1.22)0.62 (0.49 to 0.78)0.39 (0.31 to 0.51)
p Value0.590.86<0.0001<0.0001
Total wrist arthroplasty/wrist arthrodesis
Total number2351393517
Adjusted rate (95% CI)8.3 (4.8 to 11.7)15.4 (11.2 to 19.6)10.4 (7.1 to 13.7)8.0 (5.3 to 10.6)3.5 (1.8 to 5.2)
Adjusted rate ratio (95% CI)1.00 (reference)1.91 (1.17 to 3.12)1.25 (0.74 to 2.09)0.96 (0.57 to 1.63)0.43 (0.23 to 0.80)
p Value0.020.410.890.008
Age ≤60 years
Total knee arthroplasty
Total number25232934337831393621
Adjusted rate (95% CI)553.9 (530.8 to 577.0)581.2 (559.7 to 602.7)636.0 (614.5 to 657.4)555.2 (535.8 to 574.6)577.8 (558.9 to 596.7)
Adjusted rate ratio (95% CI)1.00 (reference)1.05 (0.99 to 1.10)1.13 (1.08 to 1.19)0.99 (0.94 to 1.04)1.04 (0.98 to 1.09)
p Value0.10<0.00010.590.19
Total hip arthroplasty
Total number15682303283726712677
Adjusted rate (95% CI)331.5 (314.2 to 348.8)456.2 (437.1 to 475.2)534.0 (514.3 to 553.7)472.4 (454.6 to 490.3)441.3 (424.5 to 458.1)
Adjusted rate ratio (95% CI)1.00 (reference)1.32 (1.24 to 1.41)1.53 (1.44 to 1.62)1.35 (1.27 to 1.44)1.26 (1.19 to 1.34)
p Value<0.0001<0.0001<0.0001<0.0001
Total ankle arthroplasty/ankle arthrodesis
Total number151220242183165
Adjusted rate (95% CI)30.2 (25.1 to 35.2)39.8 (34.4 to 45.2)44.9 (39.2 to 50.6)32.4 (27.7 to 37.1)25.9 (21.9 to 29.9)
Adjusted rate ratio (95% CI)1.00 (reference)1.34 (1.09 to 1.65)1.45 (1.18 to 1.78)1.04 (0.84 to 1.30)0.86 (0.69 to 1.07)
p Value0.0060.00040.700.19
Total wrist arthroplasty/wrist arthrodesis
Total number3679794818
Adjusted rate (95% CI)7.4 (4.9 to 9.9)15.0 (11.6 to 18.4)14.6 (11.4 to 17.9)8.5 (6.1 to 10.9)2.7 (1.4 to 4.0)
Adjusted rate ratio (95% CI)1.00 (reference)2.02 (1.36 to 2.99)1.96 (1.32 to 2.91)1.13 (0.73 to 1.75)0.39 (0.22 to 0.69)
p Value0.00050.00090.580.0012
  • * Adjusted rates per 100 000 people.