Table 3

Cause of death in patients with baseline RA-ILD

DMARD cohort (n=14)Anti-TNF cohort (n=70)*
RA-ILD on death certificate
 ILD as immediate cause of death1 (7)15 (22)
 ILD present on death certificate2 (14)24 (35)
Underlying cause of death by ICD-10 chapter
 Certain infectious and parasitic diseases3 (4)
 Neoplasms5 (36)9 (13)
 Diseases of the blood and blood-forming organs1 (1)
 Endocrine, nutritional and metabolic diseases1 (1)
 Circulatory4 (29)13 (19)
 Respiratory3 (21)20 (29)
 Digestive2 (3)
 Musculoskeletal and connective tissue2 (14)17 (24)
 Genitourinary2 (3)
 External causes1 (1)
 Missing1 (1)
  • Figures represent number (%) of deaths.

  • * One missing cause of death in anti-TNF cohort. Percentages represent proportion of 69 patients with a reported cause of death.

  • DMARD, disease-modifying antirheumatic drug; ILD, interstitial lung disease; RA-ILD, rheumatoid arthritis-associated ILD; TNF, tumour necrosis factor.