Table 2

Change in patient outcomes during 1-year follow-up

Patient outcomesDAS-driven therapy(n = 234)Routine care(n = 201)p Value
Health Assessment Questionnaire*−0.70 (−0.7)−0.55 (−0.7)0.029
Disease Activity Score in 28 joints*−2.7 (1.5)−1.9 (1.5)<0.001
Erythrocyte sedimentation rate (mm/h)†−19 (−6 to −37)−13 (−3 to −28)0.011
Total Sharp/van der Heijde score
    Median (IQR)2.0 (0.0 to 7.0)1.0 (0.0 to 3.5)0.006
    Mean (SD)5.7 (11.9)3.4 (7.2)
Erosion score
    Median (IQR)1.0 (0.0–4.0)0.5 (0.0–3.0)0.259
    Mean (SD)3.1 (6.7)2.4 (4.7)
Narrowing score
    Median (IQR)0.5 (0.0–3.0)0.0 (0.0–1.0)<0.001
    Mean (SD)2.6 (6.3)1.0 (3.0)
  • *Mean (standard deviation); †median (interquartile range).

  • DAS, Disease Activity Score.