Change in patient outcomes during 1-year follow-up
Patient outcomes | DAS-driven therapy(n = 234) | Routine care(n = 201) | p Value |
Health Assessment Questionnaire* | −0.70 (−0.7) | −0.55 (−0.7) | 0.029 |
Disease Activity Score in 28 joints* | −2.7 (1.5) | −1.9 (1.5) | <0.001 |
Erythrocyte sedimentation rate (mm/h)† | −19 (−6 to −37) | −13 (−3 to −28) | 0.011 |
Total Sharp/van der Heijde score | |||
Median (IQR) | 2.0 (0.0 to 7.0) | 1.0 (0.0 to 3.5) | 0.006 |
Mean (SD) | 5.7 (11.9) | 3.4 (7.2) | |
Erosion score | |||
Median (IQR) | 1.0 (0.0–4.0) | 0.5 (0.0–3.0) | 0.259 |
Mean (SD) | 3.1 (6.7) | 2.4 (4.7) | |
Narrowing score | |||
Median (IQR) | 0.5 (0.0–3.0) | 0.0 (0.0–1.0) | <0.001 |
Mean (SD) | 2.6 (6.3) | 1.0 (3.0) |
*Mean (standard deviation); †median (interquartile range).
DAS, Disease Activity Score.