RR of RA overall, ACPA-positive RA and ACPA-negative RA according to different kinds of vaccinations up to 5 years before RA onset
Kind of vaccination | Cases/controls | OR (95% CI)* | |
---|---|---|---|
Total RA | Flu | 272/259 | 1.1 (0.9 to 1.3) |
Tetanus | 170/179 | 1.0 (0.8 to 1.2) | |
Diphtheria | 71/70 | 1.0 (0.7 to 1.4) | |
Tickborne encephalitis | 91/112 | 0.8 (0.6 to 1.1) | |
Hepatitis (A, B, C) | 105/124 | 0.9 (0.7 to 1.2) | |
Polio | 29/31 | 1.1 (0.6 to 1.8) | |
Pneumococcus | 22/22 | 1.0 (0.5 to 1.9) | |
No vaccination (ref) | 1269/1367 | 1.0 | |
ACPA-positive RA† | Flu | 158/259 | 1.0 (0.8 to 1.3) |
Tetanus | 105/179 | 1.0 (0.7 to 1.2) | |
Diphtheria | 41/70 | 0.9 (0.6 to 1.4) | |
Tickborne encephalitis | 53/114 | 0.7 (0.5 to 1.0) | |
Hepatitis (A, B, C) | 68/124 | 0.9 (0.7 to 1.2) | |
Polio | 14/31 | 0.8 (0.4 to 1.4) | |
Pneumococcus | 12/22 | 0.9 (0.5 to 1.9) | |
No vaccination (ref) | 792/1367 | 1.0 | |
ACPA-negative RA† | Flu | 107/259 | 1.1 (0.9 to 1.5) |
Tetanus | 63/179 | 1.0 (0.7 to 1.4) | |
Diphtheria | 30/70 | 1.3 (0.8 to 2.0) | |
Tickborne encephalitis | 33/112 | 0.8 (0.5 to 1.2) | |
Hepatitis (A, B, C) | 36/124 | 0.8 (0.6 to 1.2) | |
Polio | 14/31 | 1.3 (0.7 to 2.5) | |
Pneumococcus | 9/22 | 1.0 (0.5 to 2.3) | |
No vaccination (ref) | 460/1367 | 1.0 |