Type I psoriasis (n=519) | Type II psoriasis (n=176) | Seronegative (n=328) | ||||||||
---|---|---|---|---|---|---|---|---|---|---|
SNP | Genotype | Count (frq) | ptrend | OR (CI) | Count (frq) | ptrend | OR (CI) | Count (frq) | ptrend | OR (CI) |
rs4085613 | CC | 234 (45.2) | 1.16 (1.01 to 1.33) | 85 (48.3) | 1.15 (0.92 to 1.45) | 157 (47.9) | 1.23 (1.04 to 1.47) | |||
CA | 240 (46.3) | 0.03 | 70 (39.8) | 0.22 | 143 (43.6) | 0.015 | ||||
AA | 44 (8.3) | 21 (11.9) | 28 (8.5) | |||||||
rs4112788 | CC | 233 (44.9) | 1.16 (1.01 to 1.33) | 85 (48.3) | 1.17 (0.93 to 1.47) | 156 (47.6) | 1.24 (1.04 to 1.47) | |||
CT | 243 (46.8) | 0.03 | 71 (40.3) | 0.18 | 145 (44.2) | 0.014 | ||||
TT | 43 (8.3) | 20 (11.4) | 27 (8.2) |
Control frequencies are those reported in the UK analysis reported in table 1.
frq, frequency; n, number in subgroup; SNP, single nucleotide polymorphism.