Table 1

Characteristics at baseline according to outcome, incident or enlarging BML in either the femoral or tibial condyle of the same compartment as the meniscal exposure variable

Incident or enlarging BML in medial compartment
Yes (n=280)No (n=1064)
Age, mean±SD years62.7±8.261.9±7.8
Female knee, n (%)160 (57)639 (60)
Body mass index, kg/m2, mean±SD kg/m230.3±4.729.9±4.8
PASE, mean±SD177±85182±90
Radiographic tibiofemoral osteoarthritis, n (%)171 (61)414 (39)
Medial tibiofemoral JSN grade ≥1, n (%)186 (67)341 (32)
Mechanical axis, n (%)
 Varus (<179°)183 (66)468 (44)
 Neutral (179–180°)65 (24)354 (34)
 Valgus (>180°)28 (10)231 (22)
Medial meniscal pathology, n (%)209 (75)534 (50)
 Meniscal lesion, n (%)162 (58)346 (33)
 Meniscal extrusion, n (%)174 (64)439 (41)
Medial BML, n (%)155 (56)335 (31)
Cartilage lesion in medial compartment, n (%)239 (86)672 (63)
Incident or enlarging BML in medial compartment
Yes (n=280)No (n=1064)
Age, mean±SD years62.6±8.562.0±7.8
Female knee, n (%)83 (66)714 (59)
Body mass index, kg/m2, mean±SD kg/m229.1±4.730.1±4.8
PASE, mean±SD170±73183±90
Radiographic tibiofemoral osteoarthritis, n (%)74 (59)510 (42)
Lateral tibiofemoral JSN grade ≥1, n (%)47 (38)94 (8)
Mechanical axis, n (%)
 Varus (<179°)43 (35)608 (51)
 Neutral (179°–180°)34 (27)383 (32)
 Valgus (>180°)47 (38)212 (18)
Lateral meniscal pathology, n (%)62 (50)163 (13)
 Meniscal lesion, n (%)48 (38)116 (10)
 Meniscal extrusion, n (%)40 (33)94 (8)
Lateral BML, n (%)53 (42)192 (16)
Cartilage lesion in lateral compartment, n (%)100 (80)532 (44)
  • Missing values: medial (n=3) and lateral (n=3) tibiofemoral joint space narrowing (JSN) grade, mechanical axis (n=15), medial (n=11) and lateral (n=10) meniscal extrusion, incomplete bone marrow lesion (BML) status in one condyle in the medial compartment (n=1), cartilage lesion in the medial (n=2) and lateral (n=1) compartment.

  • PASE, physical activity scale for the elderly (the higher score the higher the physical activity level).