Correlation between baseline and changes in BML scores and cartilage volume, baseline and changes in BML and WOMAC pain scores
| Global* | Medial compartment* | Lateral compartment* | Femoropatellar compartment* | |
|---|---|---|---|---|
| Baseline and changes in BML scores and cartilage volume | ||||
| BL | −0.109, 0.012 (0.170) | −0.242, 0.058 (0.002) | −0.284, 0.080 (<0.001) | −0.283 (<0.001) |
| Change from BL (months) | ||||
| 6 | 0.105, 0.011 (0.185) | −0.002, <0.001, (0.978) | 0.082, 0.007 (0.300) | 0.052 (0.512) |
| 12 | −0.176, 0.031 (0.026) | −0.185, 0.034 (0.019) | −0.067, 0.004 (0.404) | −0.107 (0.178) |
| 24 | 0.069, 0.005 (0.413) | 0.008, <0.001 (0.921) | −0.043, 0.002 (0.367) | 0.003 (0.970) |
| Baseline and changes in BML and WOMAC pain scores | ||||
| BL | −0.131, 0.017 (0.097) | −0.149, 0.022 (0.059) | 0.102, 0.010 (0.198) | −0.105 (0.187) |
| Change from BL (months) | ||||
| 6 | −0.040, 0.002 (0.619) | 0.072, 0.005 (0.364) | −0.065, 0.004 (0.412) | −0.216 (0.006) |
| 12 | −0.036, 0.001 (0.649) | −0.026, 0.001 (0.748) | 0.066, 0.004 (0.408) | −0.239 (0.002) |
| 24 | −0.085, 0.007 (0.311) | −0.067, 0.004 (0.426) | 0.064, 0.004 (0.445) | −0.154 (0.067) |
↵* Pearson r correlation coefficients, R2 and the associated p values in parentheses are presented. A negative parameter sign means that BML score progression was associated with less variable progression.
BL, baseline; BML, bone marrow lesion; WOMAC, Western Ontario and McMaster Universities Osteoarthritis Index.