Clinical and demographic data of patients with rheumatoid arthritis according to clinical status of biopsied joint
| Moderate arthritis(n = 12) | Severe arthritis(n = 12) | |
| Median (range) age (years) | 61 (41–75) | 59 (45–83) |
| Gender (F/M) | 5/7 | 8/4 |
| Rheumatoid factor positivity (%) | 92 | 100 |
| Mean (range) disease duration (years) | 10 (3–29) | 11 (3–26) |
| Mean (SD) DAS | 5.0 (1.0) | 5.5 (1.5) |
| Median (range) number of previous DMARDs | 4 (2–8) | 5 (2–7) |
| Knee joint examination | ||
| Pain at rest (n) | 2 | 9 |
| Pain at inspection (n) | 6 | 12 |
| Median (range) score* | 1 (0–2) | 2 (1–3) |
| Swelling (n) | 9 | 12 |
| Median (range) score† | 1 (0–1) | 2.5 (2–3) |
| Effusion (n) | 5 | 12 |
*Pain score: 0 = none, 1 = pain reported on asking, 2 = patient winces, 3 = patient withdraws.
†Swelling score: 0 = absent, 1 = mild, 2 = moderate, loss of bony loss or bony contour, 3 = severe bulging.
DAS, disease activity score; DMARDs, disease-modifying antirheumatic drugs.