Outcome measure scores of patients with SSc
| Scores | Whole group (n = 213) | DU group (n = 67) | No DU group (n = 146) | p Value* | ||||||
| Mean (SD) | Min | Max | Mean (SD) | Min | Max | Mean (SD) | Min | Max | ||
| HFI (range 4–42) | 20.30 (22.76) | 1 | 40 | 23.92 (12.05) | 2 | 40 | 18.69 (26.20) | 4 | 40 | 0.048 |
| Kapandji (range 0–100) | 77.87 (20.13) | 13 | 100 | 70.09 (22.64) | 13 | 100 | 81.57 (17.84) | 36 | 100 | 0.001 |
| CHFS (range 0–90) (n = 209) | 20.15 (19.57) | 0 | 87 | 27.38 (20.68) | 2 | 86 | 16.73 (18.19) | 0 | 87 | 0.0001 |
| HAQ (range 0–3) | 1.02 (0.73) | 0 | 3 | 1.21 (0.72) | 0 | 2.75 | 0.93 (0.71) | 0 | 3 | 0.008 |
| Karnofsky performance status (range 0–100) | 78.43 (12.01) | 50 | 100 | 77.01 (11.28) | 50 | 100 | 79.15 (12.34) | 50 | 100 | 0.216 |
| SF-36 PCS (range 0–100) (n = 179) | 36.98 (11.00) | 14 | 81.66 | 35.86 (9.39) | 15.41 | 63.23 | 37.68 (11.66) | 14 | 79.66 | 0.264 |
| SF-36 MCS (range 0–100) (n = 179) | 42.09 (11.70) | 15.64 | 76.91 | 39.58 (9.54) | 15.64 | 60.32 | 43.39 (12.53) | 18.48 | 76.91 | 0.026 |
| SF-36 physical functioning (range 0–100) | 53.89 (24.60) | 0 | 100 | 51.95 (26.46) | 0 | 100 | 55.23 (23.43) | 0 | 100 | 0.421 |
| SF-36 physical role (range 0–100) | 32.44 (39.38) | 0 | 100 | 33.05 (43.16) | 0 | 100 | 55.23 (23.43) | 0 | 100 | 0.923 |
| SF-36 emotional role (range 0–100) | 43.16 (43.59) | 0 | 100 | 35.59 (43.27) | 0 | 100 | 32.41 (37.59) | 0 | 100 | 0.09 |
| SF-36 social functioning (range 0–100) | 59.35 (22.40) | 0 | 100 | 56.99 (21.05) | 0 | 100 | 47.31 (43.41) | 0 | 100 | 0.284 |
| SF-36 bodily pain (range 0–100) | 44.63 (21.23) | 0 | 100 | 42.15 (21.15) | 0 | 90 | 60.71 (23.03) | 0 | 90 | 0.249 |
| SF-36 mental health (range 0–100) | 56.11 (18.34) | 8 | 100 | 53.69 (19.28) | 8 | 100 | 46.06 (21.23) | 0 | 100 | 0.235 |
| SF-36 vitality (range 0–100) | 39.82 (17.11) | 5 | 95 | 40.76 (17.71) | 5 | 95 | 57.27 (17.90) | 10 | 85 | 0.648 |
| SF-36 general health perception (range 0–100) | 40.16 (17.53) | 5 | 82 | 39.03 (17.37) | 5 | 79 | 39.53 (17.34) | 10 | 74 | 0.495 |
| MHISS (range 0–48) | 19.30 (10.98) | 0 | 48 | 23.00 (10.80) | 2 | 48 | 17.50 (10.58) | 0 | 38 | 0.001 |
| Aesthetic burden (range 0–10) (n = 148) | 4.66 (2.59) | 0 | 10 | 6.10 (2.20) | 0 | 10 | 3.90 (2.40) | 0 | 9 | 0.0001 |
| Perceived individualised handicap (MACTAR) (range 0–30) (n = 162) | 20.00 (6.88) | 7 | 30 | 20.36 (5.23) | 9 | 30 | 20.19 (7.64) | 7 | 30 | 0.865 |
| Anxiety (HADa) (range 0–21) (n = 211) | 9.68 (4.39) | 1 | 20 | 10.16 (4.90) | 1 | 19 | 9.45 (4.15) | 0 | 19 | 0.303 |
| Depression (HADd) (range 0–21) (n = 211) | 6.85 (4.03) | 0 | 21 | 7.52 (3.62) | 0 | 16 | 6.52 (4.19) | 0 | 21 | 0.095 |
*DU vs no DU.
CHFS, Cochin hand function scale; DU, digital ulcer; HAD, Hospital Anxiety and Depression scale for anxiety (HADa) and depression (HADd); HAQ, Health Assessment Questionnaire; sHAQ, Health Assessment Questionnaire for scleroderma; HFI, hand function index (first nine items of the Keitel index); MCS, mental component; MACTAR, McMaster-Toronto Arthritis Patient Preference Disability Questionnaire; PCS, physical component; SF-36, Medical Outcomes Study Short-Form 36-item; SSc, systemic sclerosis.