Table 1 Details and clinical characteristics of the study participants
Allopurinol (n = 36)Benzbromarone (n = 29)
Age (years)58.6 (12.3)59.6 (11.3)
Male (%)8183
Tophaceous gout (%)5348
Recurrent flares (%)
    0–2/year1817
    3–5/year5950
    >5/year2233
Body mass index (kg/m2)29.4 (4.8)30.5 (6.9)
cCrCl (%)
    30–50 ml/min(3 excluded)(0 excluded)
    50–80 ml/min2239
    >80 ml/min7861
Research site (%)
    Medisch Centrum Leeuwarden2824
    Ziekenhuisgroep Twente4145
    Medisch Spectrum Twente3131
Urate characteristics
    sUr (mmol/l)0.54 (0.09)0.51 (0.08)
        Range0.39–0.830.34–0.70
    uUr (mmol/day)3.4 (1.3)3.4 (1.3)
        Range1.5–7.71.3–6.3
    UrCl (ml/min/1.73 m2)3.7 (1.3)3.9 (1.3)
        Range1.5–6.81.6–6.4
Excretor type (%)
    Underexcretor9489
    Normal excretor33
    Overproducer38
  • Data are mean (SD) or percentage, unless stated otherwise.

  • cCrCl, calculated creatinine clearance; sUr, serum urate; UrCl, urate clearance; uUr, urate excreted in urine.