Table 1

Comparison of clinical, metrological and laboratory outcomes at baseline and week 6

VariablesBaseline Median (range)Week 6 Median (range)
BASDAI5.8 (2.5–9.5)3 (1.3–9.4)**
BASFI6.3 (3.5–93.1)4.7 (1.64–93.1)**
ASQoL13 (1–18)10 (0–15)**
Pain (day)6.5 (1.8–9.7)2.8 (0.8–9.7)**
Pain (night)7.4 (1.5–9.6)2.6 (0.1–9.6)**
Fatigue6.5 (1.9–9.9)4.2 (1.4–9.7)**
Patient’s assessment of disease activity6.1 (2–10)3.8 (0.6–9.9)**
Doctor’s assessment of disease activity4.5 (1.8–8.7)2.5 (0.7–8.7)**
Early morning stiffness (min)90 (5–180)30 (0–180)**
Tender joint count1.5 (0–30)1 (0–11)*
Swollen joint count0 (0–10)0 (0–11)
MASES2 (0–9)1 (3–7)*
Schober’s test (cm)2 (0–7)3 (0–6)**
Occiput wall (cm)0 (0–16.5)1.5 (0–17)
Right lateral flexion (cm)10 (1–18)12.5 (1–24.5)**
Left lateral flexion (cm)8 (2–19)11.5 (1–22)
CRP (mg/l)17 (5–118)10.5 (5–38)
ESR (mm/1st h)14.5 (2–46)9 (2–30)*
  • *p<0.05; **p<0.001.

  • ASQoL, Ankylosing Spondylitis Quality of Life questionnaire; BASDAI, Bath Ankylosing Spondylitis Disease Activity Index; BASFI, Bath Ankylosing Spondylitis Functional Index; CRP, C-reactive protein; ESR, erythrocyte sedimentation rate; MASES, Maastricht Ankylosing Spondylitis Enthesitis Score (MASES).