Table 3

Bone marrow lesion and cartilage status in subregions at 30-month follow-up

Cartilage status at 30-month follow-up in subregionsStable BMLs (n = 151; 34.3%)Decrease of BMLs (n = 41; 9.3%)Resolution of BMLs (n = 178; 40.5%)Progression of BMLs (n = 70; 15.9%)No BML at baseline and follow-up (n = 4687; 96.3%)New BMLs (n = 182; 3.7%)
Increase in cartilage score, n (%)41 (27.2)12 (29.3)50 (28.1)36 (51.4)281 (6.0)101 (55.5)
Adjusted* OR of cartilage loss (95% CI)1.0 (Reference)1.2 (0.5 to 1.6)0.9 (0.5 to 1.6)2.8 (1.5 to 5.2)0.2 (0.1 to 0.3)3.5 (2.1 to 5.9)
  • *Adjusted for gender, age, body mass index and Kellgren and Lawrence grade at baseline.

  • BML, bone marrow lesion; 95% CI, 95% confidence interval; OR, odds ratio.