Table 3 Mean change and effect size (standardised response mean) in the International Classification of Functioning, Disability and Health (ICF) Core Set for rheumatoid arthritis (RA) components and health status, utility (Short-Form 6D (SF-6D)) and disease activity (28-joint Disease Activity Score (DAS28)) over 6 months with disease-modifying antirheumatic drug (DMARD) treatment presented for patients with and without improvement in health
All patients (n = 46)Patients with improved health (n = 27)Patients without improved health (n = 19)p Value*
ChangeEffect sizeChangeEffect sizeChangeEffect size
ICF: Body Functions−3.1 (5.3)0.59−4.5 (5.0)0.85−1.2 (5.2)0.220.03
ICF: Body Structures−1.8 (4.5)0.41−2.3 (4.1)0.50−1.3 (5.1)0.270.47
ICF: Activities and Participation−4.3 (6.0)0.71−5.1 (6.7)0.85−3.1 (4.8)0.510.27
ICF: Environmental Factors−1.8 (3.3)0.53−2.0 (3.6)0.59−1.5 (3.0)0.440.63
All ICF categories−11.0 (13.2)0.83−13.9 (13.5)1.05−7.0 (11.9)0.530.08
MHAQ−0.16 (0.46)0.35−0.28 (0.43)0.600.01 (0.45)0.010.04
SF-36 PCS3.5 (8.7)0.416.4 (7.9)0.740.3 (8.6)0.030.01
SF-36 MCS4.2 (11.0)0.385.1 (10.0)0.463.0 (12.2)0.280.55
SF-6D0.07 (0.12)0.560.09 (0.12)0.750.04 (0.12)0.320.17
DAS28−0.58 (0.77)0.75−0.80 (0.85)1.04−0.27 (0.53)0.340.01
  • *t Test comparing patients with improved versus patients without improved health.

  • MCS, mental component summary; MHAQ, Modified Health Assessment Questionnaire; PCS, physical component summary; SF-36, Short Form 36.