Table 1 Results of the systematic literature search for each recommendation topic
Retrieved references by systematic literature search (n)Articles included in the systematic reviews (n)
Pre-methotrexate work-up121452
Dosage and route174850
Folic acid3349
Monitoring85723
Hepatotoxicity42646
Long-term safety244988
Mono vs combination695820
Steroid-sparing agent5276
Perioperative period3034
Pregnancy21636
Total16 979304