B-cell subsets | Cut-off point (%) | Sensitivity (%) | Specificity (%) |
Bm2+Bm2′/eBm5+Bm5 | ⩾5.0 | 88.0 | 84.6 |
Bm2+Bm2′ | ⩾71.1 | 88.0 | 83.1 |
eBm5+Bm5 | ⩽13.5 | 84.0 | 83.1 |
Bm5 | ⩽7.6 | 84.0 | 80.1 |
eBm5 | ⩽6.7 | 80.0 | 72.8 |
Bm2 | ⩾59.9 | 80.0 | 75.7 |
Bm2′ | ⩾5.1 | 84.0 | 61.8 |
Bm1 | ⩽12.9 | 80.0 | 64.0 |
*Bm, mature B lymphocyte classified from Bm1 through Bm5, according to the relative membrane expression of IgD and CD38.11