Table 3

Optimal levels of B-cell subsets for the diagnosis of primary Sjögren syndrome (in decreasing order)

B-cell subsetsCut-off point (%)Sensitivity (%)Specificity (%)
Bm2+Bm2′/eBm5+Bm5⩾5.088.084.6
Bm2+Bm2′⩾71.188.083.1
eBm5+Bm5⩽13.584.083.1
Bm5⩽7.684.080.1
eBm5⩽6.780.072.8
Bm2⩾59.980.075.7
Bm2′⩾5.184.061.8
Bm1⩽12.980.064.0
  • *Bm, mature B lymphocyte classified from Bm1 through Bm5, according to the relative membrane expression of IgD and CD38.11