Table 2

Blood B-cell subsets or subset combinations (means (SD) of percentage) in patients with primary Sjögren syndrome (pSS), compared with patients with rheumatoid arthritis (RA) or systemic lupus erythematosus (SLE), and with normal controls

B-cell subsets or combinations of subsetsDisease controlsNormal controls(n = 26)
pSS(n = 25)RA(n = 54)SLE(n = 18)
Bm1*9.9 (7.5)20.2 (10.3)15.2 (14.1)21.2 (8.6)
p<0.001NSp<0.001
Bm265.2 (11.5)44.8 (15.3)48.5 (14.7)43.3 (12.1)
p<0.001p<0.001p<0.001
Bm2′12.5 (9.9)4.0 (5.2)8.0 (7.2)4.0 (2.7)
p<0.001NSp<0.001
Bm2+Bm2′77.7 (13.3)48.8 (17.5)56.5 (18.5)47.3 (4.5)
p<0.001p<0.001p<0.001
early Bm5 (eBm5)5.3 (3.2)11.0 (4.7)10.2 (4.9)13.2 (4.5)
p<0.001p<10−3p<0.001
Bm55.6 (4.3)16.9 (9.1)14.0 (8.9)15.3 (6.9)
p<0.001p<0.001p<0.001
eBm5+Bm510.9 (7.2)27.9 (12.0)24.2 (12.7)28.5 (9.1)
p<0.001p<0.001p<0.001
Bm2+Bm2′/eBm5+Bm510.7 (7.9)2.5 (2.2)3.4 (2.7)2.0 (1.1)
p<0.001p<0.001p<0.001
  • All p values are in comparison with patients with pSS.

  • *Bm, mature B lymphocyte classified from Bm1 through Bm5, according to the relative membrane expression of IgD and CD38.11