Table 2 Correlations between DAS28/ESR and PON-1 activities during TNF blockade
Baseline2 Weeks6 Months
PONAREPONAREPONARE
DAS28−0.18−0.39*−0.31**−0.47**−0.12−0.10
ESR (mm/h)−0.36*−0.36*−0.37*−0.58***−0.22−0.16
Δ PONΔ AREΔ PONΔ AREΔ PONΔ ARE
Δ DAS28−0.07−0.35*−0.02−0.02
Δ ESR (mm/h)−0.28−0.150.000.02
  • ARE, arylesterase activity; DAS28, disease activity score; ESR, erythrocyte sedimentation rate; PON, paraoxonase activity; TNF, tumour necrosis factor. *p<0.05, **p<0.01, ***p<0.001.