| Week 0 (n = 50) | Week 16 (n = 50) | p Value | Week 52 (n = 44) | p Value | |
| MIF, pg/ml (IQR) | 333 (90–1544) | 171 (60–444) | 0.020* | 145 (60–335) | 0.012* |
| Total cholesterol, mmol/l (SD) | 4.86 (1.07) | 5.06 (1.16) | 0.053 | 4.98 (1.13) | 0.301 |
| HDL-cholesterol, mmol/l (SD) | 1.52 (0.38) | 1.66 (0.38) | <0.001* | 1.62 (0.39) | 0.061 |
| LDL-cholesterol, mmol/l (SD) | 2.88 (0.95) | 2.96 (1.01) | 0.392 | 2.93 (1.02) | 0.577 |
| Triglycerides, mmol/l (SD) | 1.01 (0.51) | 0.99 (0.54) | 0.513 | 0.94 (0.43) | 0.350 |
| Apo A-I, mmol/l (SD) | 1.46 (0.25) | 1.56 (0.22) | <0.001* | 1.56 (0.21) | 0.005* |
| Apo B, mmol/l (SD) | 0.99 (0.25) | 1.00 (0.27) | 0.465 | 0.99 (0.28) | 0.816 |
| Lp(a), mmol/l (IQR) | 198 (65–356) | 175 (65–377) | <0.001* | 171 (47–375) | 0.001* |
| Total cholesterol/HDL (SD) | 3.33 (0.93) | 3.15 (0.85) | 0.034* | 3.19 0.84) | 0.272 |
| Apo B/Apo A-I (SD) | 0.70 (0.21) | 0.65 (0.20) | 0.014* | 0.65 (0.20) | 0.050 |
| Glucose, mmol/l (SD) | 5.13 (1.97) | 4.95 (1.14) | 0.847 | 5.04 (1.34) | 0.930 |
| CRP, mg/l (IQR) | 8.8 (4.6–19.6) | 3.8 (1.6–9.1) | <0.001* | 2.7 (1.1–5.6) | <0.001* |
Values are represented as mean (SD) or median and interquartile range (IQR).
*p Values <0.05 (two-sided) are significant.
Apo, apolipoprotein; CRP, C-reactive protein; HDL, high-density lipoprotein; LDL, low-density lipoprotein; Lp(a), lipoprotein (a); MIF, macrophage migration inhibitory factor.