Table 1 Inflammatory and lipid parameters investigated in the group of rheumatoid arthritis patients during anti-TNF therapy (n  =  45)
Baseline2 Weeks6 Months
DAS28 (SD)5.26 (1.24)3.82 (1.42)***4.23 (1.26)***
ESR, mm/h (SD)31 (19.2)20.7 (17.8)***24 (15.1)***
BMI, kg/m2 (SD)25.7 (5.5)25.6 (5.4)25.7 (5.5)
Lipids
    Total cholesterol, mmol/l (SD)5.56 (1.03)5.81 (1.04)**5.60 (0.99)
    LDL-cholesterol, mmol/l (SD)3.66 (0.87)3.74 (0.88)3.60 (0.79)
    HDL-cholesterol, mmol/l (SD)1.34 (0.32)1.43 (0.37)**1.29 (0.34)
    Total cholesterol/HDL cholesterol (SD)4.27 (1.15)4.34 (1.20)4.51 (1.27)*
    LDL cholesterol/HDL cholesterol (SD)2.82 (0.91)2.76 (1.05)2.94 (1.01)
    Apolipoprotein AI, mg/l (SD)1504 (309)1586 (299)**1474 (299)
    Triglycerides, mmol/l (SD)1.38 (0.58)1.49 (0.63)1.61 (0.83)*
  • Results are presented as mean (SD); *p<0.05, **p<0.01, ***p<0.001 versus baseline.

  • BMI, body mass index; DAS28, disease activity score; ESR, erythrocyte sedimentation rate; HDL, high-density lipoprotein; LDL, low-density lipoprotein; TNF, tumour necrosis factor.