Table 1 Comparison of frequencies of symptoms and complications in patients with IgG4-positive multiorgan lymphoproliferative syndrome (IgG4+MOLPS) and those with typical Sjögren’s syndrome (SS)
IgG4+MOLPSTypical SSJapanese*p Value†p Value‡p Value§
All(n = 64)Women(n = 33)Men(n = 31)All(n = 31)Women(n = 29)
Xerophthalmia32.8% (21)42.4% (14)22.6% (7)93.5% (29)93.1% (27)<0.001<0.0010.114
Xerostomia37.5% (24)45.5% (15)29.0% (9)87.1% (27)86.2% (25)<0.0010.0010.205
Arthralgia15.6% (10)15.2% (5)16.1% (5)48.4% (15)51.7% (15)0.0010.0021.000
Allergic rhinitis40.6% (26)54.5% (18)25.8% (8)6.5% (2)6.9% (2)5–10%0.001<0.0010.024
Bronchial asthma14.1% (9)18.2% (6)9.7% (3)3.2% (1)3.4% (1)3–5%0.1580.1090.476
Autoimmune pancreatitis17.2% (11)3.0% (1)32.3% (10)0.0% (0)0.0% (0)<0.001%0.0140.5320.002
Interstitial nephritis17.2% (11)9.1% (3)25.8% (8)6.5% (2)6.9% (2)<0.005%0.2101.0000.074
Interstitial pneumonitis9.4% (6)9.1% (3)9.7% (3)32.3% (10)31.0% (9)<0.005%0.0080.0511.000
  • Incidence rates (numbers of positive patients) are shown.

  • *Incidence rates in Japanese population.

  • †All IgG4+MOLPS vs all typical SS.

  • ‡Female IgG4+MOLPS vs female typical SS.

  • §Female vs male IgG4+MOLPS.