Table 1 Levels of core set of disease activity measures and derived disease activity indices at both time points and test–retest reliability
Included in index*T1T2ChangeSpearman rICC*SDDMDC%
TJC28D S C3.2 (4.7)3.6 (3.7)0.4 (2.5)0.760.834.817.1%
SJC28D S C1.6 (2.4)2.5 (2.9)0.9 (0.9)0.740.783.512.5%
PhysGlobS C11.7 (9.6)13.1 (8.2)1.4 (5.8)0.690.7911.311.3%
PatGlobD S C R30.1 (22.3)25.7 (18.0)4.4 (13.3)0.800.7826.226.2%
FunctionR1.50 (0.43)1.46 (0.39)0.04 (0.11)0.980.960.227.3%
PainR29.5 (23.7)25.8 (22.0)3.7 (11.4)0.830.8822.322.3%
ESRD15.6 (12.9)15.5 (13.3)0.1 (4.2)0.840.958.08.0%
CRPS9.1 (14.4)8.9 (14.4)0.2 (3.4)0.710.976.96.9%
DAS283.12 (1.27)3.31 (1.10)0.19 (0.67)0.850.851.3214.4%
SDAI9.88 (9.23)10.84 (8.24)0.96 (4.21)0.870.888.269.6%
CDAI8.97 (9.10)9.96 (8.10)0.99 (4.10)0.890.898.0510.6%
RAPID32.54 (1.77)2.22 (1.63)0.32 (0.76)0.880.901.4814.8%
RADAI3.22 (1.87)2.91 (1.93)0.32 (0.76)0.890.921.4914.9%
  • *D, DAS28; S, SDAI; C, CDAI; R, RAPID3. All p<0.01

  • Values are mean (standard deviation)

  • CDAI, Clinical Disease Activity Index; CRP, C-reactive protein; DAS28, 28-joint Disease Activity Score; ESR, erythrocyte sedimentation rate; MDC%, minimum detectable change; PatGlob, patient global assessment of disease activity; PhysGlob, physician/assessor global estimate of disease activity; RADAI, Rheumatoid Arthritis Disease Activity Index; RAPID3, Routine Assessment of Patient Index Data; SDAI, Simple Disease Activity Index; SDD, smallest detectable difference; SJC, swollen joint count; TJC, tender joint count.