Table 2 Maternal, pregnancy and infant characteristics and risk of later RA and JIA, univariate OR with 95% CI
RAJIA
Cases n  =  333Controls n  =  1332OR (95% CI)Cases n  =  3334Controls n  =  13 336OR (95% CI)
Maternal age, years
    <251204821.0 (0.8 to 1.3)101740771.0 (0.9 to 1.1)
    25–291295191125349671
    30–34622421.0 (0.7 to 1.4)77331181.0 (0.9 to 1.1)
    35+22891.0 (0.6 to 1.7)29111741.0 (0.9 to 1.2)
Maternal civil status
    Married2108311223790881
    Other1084291.0 (0.7 to 1.3)72028471.0 (0.9 to 1.1)
No of older siblings
    01405971145758441
    1–21756781.1 (0.9 to 1.4)170567171.0 (0.9 to 1.1)
    ⩾318571.4 (0.8 to 2.4)1727740.9 (0.8 to 1.1)
Season of birth
    January–March883660.9 (0.6 to 1.3)91235321.08 (1.0 to 1.2)
    April–June94355186035981
    July–September773250.9 (0.6 to 1.2)79732291.0 (0.9 to 1.2)
    October–December742861.0 (0.7 to 1.4)76529771.1 (1.0 to 1.2)
Mode of delivery
    Vaginal30212101294611 9301
    Caesarean311221.0 (0.7 to 1.5)38814061.1 (1.0 to 1.3)
Type of birth
    Singletons32913091326813 0441
    Multiple birth4230.7 (0.2 to 2.0)652880.9 (0.7 to 1.2)
Birth weight, g
    <3000432260.7 (0.5 to 1.0)53321811.0 (0.9 to 1.1)
    3000–39992399101223789361
    ⩾4000501941.0 (0.7 to 1.4)55321561.0 (0.9 to 1.1)
Birth weight for gestational age*
    SGA10730.5 (0.3 to 1.0)1164701.0 (0.8 to 1.2)
    AGA30712031306112 0931
    LGA10251.6 (0.7 to 3.3)683490.8 (0.6 to 1.0)
Gestational age, days
    ⩽25813800.6 (0.7 to 1)1376670.8 (0.7 to 1.0)
    259–29327810921285111 4761
    ⩾294411541.1 (0.7 to 1.5)32611151.2 (1.03 to 1.3)
Congenital malformation
    No32812981305212 2131
    Yes5340.6 (0.2 to 1.5)773001.0 (0.8 to 1.3)
Maternal smoking†
    Non-smoking85734381
    Smoking30212631.0 (0.8 to 1.1)
    Missing198727
Apgar at 5 minutes
    ⩽65270.7 (0.3 to 1.9)342000.7 (0.5 to 1.0)
    7–812371.3 (0.7 to 2.5)1004131.0 (0.8 to 1.2)
    9–102379501280711 2311
  • *Multiple births not included. †Registration not started until 1983, which is why numbers are smaller than for other exposures. The proportion of data that was missing was similar for cases and controls. Data on maternal civil status were missing for 6% of rheumatoid arthritis (RA) cases/controls and for 11% of juvenile idiopathic arthritis (JIA) cases/controls. Data on malformations were missing for 6% of all cases and controls. Data on Apgar scores were missing for 11% of JIA cases/controls and for 23% of RA cases/controls. For all other parameters, data were missing for less than 5% of all observations. AGA, appropriate for gestational age; LGA, large for gestational age; OR, odds ratio; SGA, small for gestational age.