Table 2

Median (interquartile range) for semiquantitative and quantitative MRI measurements of the medial tibiofemoral joint in men

K/L 0 (n  =  322)Subset of K/L 0 with no cartilage lesions on MRI (n  =  169)K/L 1 (n  =  9)K/L 2 (n  =  32)K/L 3 (n  =  21)K/L 4 (n  =  12)
Medial tibia
    Volume, mm32527 (2216–2815)2520 (2240–2787)2859 (2342–2900)2519 (2415–2945)2278 (1917–2571)1394 (1190–1677)
        p Value0.190.290.04<0.001
    Subchondral bone area, cm213.66 (12.88–14.65)13.63 (12.93–14.56)14.59 (13.24–15.51)14.50 (13.63–15.06)14.29 (13.58–15.47)13.86 (12.52–15.89)
        p Value0.090.0040.050.74
    Thickness, mm1.87 (1.72–1.99)1.87 (1.72–1.98)1.85 (1.79–1.96)1.82 (1.65–1.97)1.59 (1.32–1.83)0.99 (0.84–1.19)
        p Value0.960.270.003<0.001
    WORMS score0.0 (0.0–0.0)0*1.0 (1.0–1.7)0.8 (0.3–1.5)3.3 (1.0–3.7)3.2 (1.0–5.3)
        p Value0.001<0.001<0.001<0.001
Central medial tibia‡
    Thickness, mm2.53 (2.28–2.73)2.54 (2.26–2.73)2.51 (2.31–2.67)2.32 (2.04–2.60)2.07 (1.70–2.41)0.85 (0.54–1.17)
        p Value0.650.007<0.001<0.001
    WORMS score0.0 (0.0–0.0)0*2.5 (0.0–4.0)3.0 (3.0–4.0)5.0 (3.5–6.0)6.0 (5.0–6.0)
        p Value0.001<0.001<0.001<0.001
Central medial femur
    Volume, mm31316 (1154–1523)1321 (1166–1502)1378 (1191–1639)1141 (1018–1417)823 (641–1252)361 (336–538)
        p Value0.720.06<0.001<0.001
    Subchondral bone area, cm26.09 (5.41–6.81)6.09 (5.41–6.62)6.81 (5.19–7.04)5.97 (5.28–6.99)6.49 (5.83–6.92)5.89 (5.68–7.61)
        p Value0.400.830.180.56
    Thickness, mm2.05 (1.86–2.24)2.05 (1.88–2.22)2.06 (1.83–2.19)1.90 (1.62–2.10)1.40 (0.90–1.57)0.63 (0.42–1.01)
        p Value0.720.06<0.001<0.001
    WORMS score0.0 (0.0–2.0)0*2.0 (0.0–3.0)3.0 (3.0–4.0)5.0 (5.0–6.0)6.0 (6.0–6.0)
        p Value0.005<0.001<0.001<0.001
Central part of central medial femur†,‡
    Thickness, mm2.54 (2.20–2.82)2.54 (2.25–2.79)2.44 (2.11–2.57)2.13 (1.94–2.56)1.45 (0.90–1.73)0.34 (0.10–0.85)
        p Value0.260.001<0.001<0.001
  • p Values from Wilcoxon test are printed in italics, and all of these p values are compared with Kellgren/Lawrence (K/L) grade 0. All data are presented with the focus on K/L 2 versus 0 depicted in bold font. *By definition this group has cartilage whole-organ magnetic resonance imaging score (WORMS) 0. †No corresponding WORMS score. ‡No corresponding volume measurement.