Initial IFX (n = 117) | Delayed IFX (n = 67) | p Value | |
Stopped IFX and still DAS ⩽2.4, no. (%) | 66 (56) | 19 (29) | <0.001 |
Max dose IFX 3 mg/kg, no. | 38 | 10 | |
Max dose IFX 6 mg/kg, no. | 21 | 8 | |
Max dose IFX 7.5 mg/kg, no. | 4 | 1 | |
Max dose IFX 10 mg/kg, no. | 3 | – | |
Remained on MTX+IFX, no. (%) | 22 (19) | 27 (40) | 0.002 |
Max dose IFX 3 mg/kg, no. | 7 | 5 | |
Max dose IFX 6 mg/kg, no. | 4 | 4 | |
Max dose IFX 7.5 mg/kg, no. | 6 | 5 | |
Max dose IFX 10 mg/kg, no. | 5 | 13 | |
Failed on MTX+IFX, no. (%) | 29 (25) | 21 (31) | 0.336 |
Due to toxicity, no. | 8 | 6 | |
Due to inefficacy, no. | 21 | 13 | |
Due to other reasons, no. | – | 2 |
DAS, disease activity score; IFX, infliximab; MTX, methotrexate.