Table 1

Median (interquartile range) for semiquantitative and quantitative MRI measurements of the medial tibiofemoral joint in women

K/L 0 (n  =  398)Subset of K/L 0 with no cartilage lesions on MRI (n  =  235)K/L 1 (n  =  24)K/L 2 (n  =  49)K/L 3 (n  =  34)K/L 4 (n  =  10)
Medial tibia
    Volume, mm31684 (1498–1895)1660 (1507–1853)1737 (1499–1892)1870 (1675–2111)1772 (1381–2062)1263 (930–1540)
        p Value0.84<0.0010.60<0.001
    Subchondral bone area, cm210.59 (9.86–11.35)10.50 (9.86–11.28)10.43 (10.00–11.10)11.46 (10.87–11.97)11.43 (10.78–12.29)11.75 (10.76–12.89)
        p Value0.71<0.001<0.001<0.001
    Thickness, mm1.60 (1.49–1.71)1.60 (1.49–1.71)1.62 (1.48–1.76)1.65 (1.52–1.85)1.50 (1.27–1.63)0.99 (0.67–1.19)
        p Value0.650.080.005<0.001
    WORMS score0.0 (0.0–0.0)0*0.0 (0.0–1.0)1.0 (0.0–2.0)2.7 (2.0–3.7)4.0 (3.7–5.0)
        p Value<0.001<0.001<0.001<0.001
Central medial tibia‡
    Thickness, mm2.13 (1.93–2.33)2.12 (1.93–2.31)2.08 (1.89–2.44)2.22 (1.83–2.44)1.73 (1.49–2.19)0.96 (0.29–1.52)
        p Value0.850.38<0.001<0.001
    WORMS score0.0 (0.0–0.0)0*0.0 (0.0–3.0)3.0 (0.0–3.0)5.0 (3.0–5.0)5.0 (5.0–6.0)
        p Value0.001<0.001<0.001<0001
Central medial femur
    Volume, mm3832 (713–978)827 (700–945)888 (674–1076)863 (710–1072)706 (509–947)249 (206–531)
        p Value0.640.200.002<0.001
    Subchondral bone area, cm24.81 (4.27–5.42)4.74 (4.20–5.32)5.03 (4.33–5.60)5.12 (4.54–6.05)5.26 (4.21–5.91)5.28 (4.48–5.74)
        p Value0.200.0070.150.31
    Thickness, mm1.65 (1.53–1.82)1.64 (1.53–1.78)1.58 (1.48–1.81)1.63 (1.41–1.83)1.30 (1.01–1.55)0.47 (0.35–1.13)
        p Value0.460.30<0.001<0.001
    WORMS score0.0 (0.0–2.0)0*2.5 (0.0–3.0)3.0 (2.5–4.0)5.0 (4.0–5.0)6.0 (5.0–6.0)
        p Value0.001<0.001<0.001<0.001
Central part of central medial femur†,‡
    Thickness, mm2.00 (1.80–2.22)2.00 (1.78–2.18)1.83 (1.63–2.03)1.83 (1.49–2.14)1.29 (0.98–1.66)0.18 (0.06–1.13)
        p Value0.030.006<0.001<0.001
  • p Values from Wilcoxon test are printed in italics, and all of these p values are compared with Kellgren/Lawrence (K/L) grade 0. All data are presented with the focus on K/L 2 versus 0 depicted in bold font. *By definition this group has cartilage whole-organ magnetic resonance imaging score (WORMS) 0. †No corresponding WORMS score. ‡No corresponding volume measurement.