Table 1 Demographic and disease characteristics at the time of inclusion in the BeSt study of patients treated with initial IFX and delayed IFX
Initial IFX (nā€Š=ā€Š117)Delayed IFX (nā€Š=ā€Š67)p Value
Female sex (%)68810.057
Age at diagnosis, mean (SD)53.8 (14.1)49.8 (12.4)0.054
RF positive (%)64750.141
Symptom duration (weeks), median (IQR)23 (13 to 45)29 (17 to 56)0.175
Disease duration (weeks), median (IQR)3 (1 to 5)2 (1 to 5)0.069
Tender joints (no.), mean (SD)13 (6)16 (7)<0.001
Swollen joints (no.), mean (SD)14 (7)16 (6)0.049
ESR, median (IQR)35 (19 to 56)40 (22 to 68)0.157
DAS, mean (SD)4.29 (0.8)4.73 (0.8)0.001
HAQ, mean (SD)1.36 (0.7)1.49 (0.5)0.159
Erosion score, median (IQR)2.0 (0.5 to 5.0)1.5 (0.5 to 3.5)0.294
Narrowing score, median (IQR)1.5 (0.0 to 3.8)1.5 (0.0 to 4.0)0.953
Total Sharp score, median (IQR)4.0 (1.5 to 9.0)3.0 (1.0 to 7.5)0.568
  • Best, Behandel Stratagieen (treatment strategies); DAS, disease activity score; ESR, erythrocyte sedimentation rate; HAQ, health assessment questionnaire; IFX, infliximab; IQR, interquartile range; RF, rheumatoid factor.