Table 5 Mean and minimum joint space narrowing (JSN)

Month	Licofelone		Naproxen		p Value
Month	n	Mean (SD)	n	Mean (SD)	p Value
Mean JSN
ITT
Baseline	147	4.14 (1.62)	154	4.10 (1.62)	0.846
Change from baseline
12	147	−0.16 (0.42)	154	−0.23 (0.54)	0.223
24	147	−0.35 (0.55)	154	−0.39 (0.59)	0.544

ATP
Baseline	82	4.10 (1.96)	79	4.09 (1.84)	0.976
Change from baseline
12	82	−0.14 (0.46)	78	−0.23 (0.62)	0.270
24	80	−0.38 (0.71)	77	−0.42 (0.77)	0.778

Minimum JSN
ITT
Baseline	147	3.36 (1.57)	154	3.31 (1.56)	0.761
Change from baseline
12	147	−0.13 (0.38)	154	−0.22 (0.47)	0.097
24	147	−0.29 (0.49)	154	−0.38 (0.54)	0.106

ATP
Baseline	82	3.32 (1.90)	79	3.31 (1.80)	0.974
Change from baseline
12	82	−0.12 (0.38)	78	−0.20 (0.52)	0.262
24	80	−0.30 (0.65)	77	−0.42 (0.70)	0.287

p Values were assessed by two sample t tests.
ATP, according to protocol; ITT, intention to treat.