1 | Damage of joints | One should mention not only the hip but also other joints. | Peripheral arthritis is usually oligoarticular and affects mainly the lower limbs. Hip involvement is reported as a bad prognostic sign |
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| | Insufficient data of non-pharmacological treatment, only 15% of studies reported effects of non-pharmacological treatment in AS |
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| Education | | Effect of isolated education for AS is not yet clear |
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| Physiotherapy | Appropriate exercise is crucial to managing AS. Regular home exercise is the basis of non-pharmacological treatment. Physiotherapy may be completed with other procedures (balneotherapy or electrotherapy) | Specific physical modalities have not been studied |
| Self-help groups | Patients who take an active interest in their condition can positively influence the outcome of AS. Using practical advice of self-help groups to manage the condition is strongly recommended by stakeholders | Self-help groups have not been studied for their effect on pain or functional outcomes |
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8 | Sulfasalazine | Comment on the role of sulfasalazine for the treatment of uveitis, inflammatory bowel disease, psoriasis | Additional to the role of sulfasalazine in peripheral arthritis associated with spondyloarthritis, sulfasalazine may play a role in the treatment of uveitis, inflammatory bowel disease, psoriasis, but there are insufficient data on these options |