Baseline characteristics | JSN progression | RR (95% CI)† | Osteophyte progression | RR (95% CI)† |
Age, years | ||||
Old age (⩾60) | 16/90 | 1 | 13/90 | 1 |
Middle age (40–60) | 17/82 | 1.2 (0.6 to 2.1) | 24/82 | 1.9 (1.0 to 3.2) |
Gender | ||||
Men | 8/37 | 1 | 3/37 | 1 |
Women | 25/135 | 0.8 (0.3 to 1.5) | 34/135 | 2.9 (1.0 to 6.4) |
Post-menopausal stage, years‡ | ||||
Late (>10) | 6/59 | 1 | 9/59 | 1 |
Early (⩽10) | 15/58 | (1.1 to 6.6) | 18/40 | 2.6 (1.0 to 4.6) |
*Risk ratios (RR; 95% CI) adjusted for age, gender and familial effect.
†Radiological progression was defined as at least one score increase in the joint space narrowing (JSN) and osteophyte progression scores of the distal interphalangeal joints, proximal interphalangeal joints, first interphalangeal joints and first carpometacarpal joints after 2 years.
‡Number of years after the final menstrual period in 117 post-menopausal women categorised based on the median value of 10 years.