Table 4 Multivariate Cox regression analyses, controlled for gender and age at onset of psoriasis and their interactions with calendar time.
Disease-related variablesHazard ratioLCLUCLp Value
Hypertension
Steroids used since last visit1.981.013.880.05
Interaction of steroids and calendar time1.690.863.310.13
Diabetes2.421.015.830.05
Logarithm of triglycerides1.431.111.860.01
PASI score (base category 0)0.03
    0<PASI⩽100.830.411.71
    10<PASI⩽200.730.271.94
    PASI >202.120.875.20
    Unknown PASI0.650.251.71
Myocardial infarction
ESR1.010.991.040.29
Interaction of ESR and gender1.010.971.040.74
Interaction of ESR and calendar time1.021.001.040.05
Interaction of ESR, gender and calendar time0.980.951.000.04
Current smoker
    Yes9.091.9342.760.01
    Unknown2.350.707.880.17
Logarithm of triglycerides1.491.012.190.04
First CVD event
Steroids used since last visit1.780.963.310.07
Interaction of steroids and calendar time1.700.903.200.10
Diabetes2.101.004.430.05
Logarithm of triglycerides1.471.171.83<0.01
PASI score (base category = 0)0.05
    0<PASI⩽101.280.612.69
    10<PASI⩽200.880.352.24
    PASI >202.711.136.51
    Unknown PASI1.450.504.19
Interaction of PASI score and calendar time0.05
    0<PASI⩽100.530.280.98
    10<PASI< = 200.670.202.32
    PASI >200.970.322.94
    Unknown PASI1.510.753.02
  • CVD, cardiovascular disease; ESR, erythrocyte sedimentation rate; LCL, lower 95% confidence limit; PASI, Psoriasis Area and Severity Index; UCL, upper 95% confidence limit.