Table 2 Baseline demographic and clinical characteristics for patients who switched to weekly adalimumab treatment and patients who received adalimumab 40 mg every other week*
CharacteristicAdalimumab 40 mg weekly (N  =  72)Adalimumab 40 mg every other week (N  =  239)
Male, n (%)46 (63.9)187 (78.2)
White, n (%)69 (95.8)230 (96.2)
Age, years (SD)46.1 (10.0)41.2 (11.8)
Disease duration, years (SD)10.7 (9.0)11.1 (9.6)
HLA-B27 positive, n (%)52 (72.2)193 (80.8)
Patient’s global assessment of disease activity, cm (SD)7.0 (2.1)6.2 (2.1)
Total back pain, cm (SD)7.2 (2.0)6.3 (2.1)
Inflammation (mean of questions 5 and 6 of the BASDAI), cm (SD)7.3 (1.9)6.5 (2.0)
BASFI, cm (SD)6.1 (2.3)5.2 (2.1)
BASDAI, cm (SD)6.9 (1.6)6.1 (1.7)
C-reactive protein, mg/dl (SD)†1.5 (1.6)2.0 (2.7)
BASMI, 0–10 (SD)4.5 (2.1)3.8 (2.2)
Chest expansion, cm (SD)2.9 (1.5)3.4 (1.9)
MASES, 0–13 (SD)8.4 (7.6)5.9 (6.7)
  • *Values are mean (SD) unless otherwise noted. †Normal range using an ultrasensitive C-reactive protein assay is 0.007–0.49 mg/dl. BASDAI, Bath Ankylosing Spondylitis Disease activity Index; BASFI, Bath Ankylosing Spondylitis Functional Index; BASMI, Bath Ankylosing Spondylitis Metrology Index; MASES, Maastricht Ankylosing Spondylitis Enthesitis Score.