ASAS workshop* (n = 20 patients) | ASAS validation study† (n = 648 patients) | |||
Sensitivity (%) | Specificity (%) | Sensitivity (%) | Specificity (%) | |
IBP according to experts: | ||||
At least 3/5 present | 91.8 | 56.3 | 95.1 | 47.5 |
At least 4/5 present | 77.0 | 91.7 | 79.6 | 72.4 |
All 5/5 present | 41.0 | 100 | 38.6 | 91.9 |
Calin criteria:‡ | ||||
At least 4/5 present | 82.0 | 73.0 | 89.9 | 52.5 |
Berlin criteria:¶ | ||||
At least 2/4 present | 83.6 | 62.5 | 70.0 | 81.4 |
Note that sensitivity and specificity refer to presence of IBP, not to diagnosis.
*ASAS Workshop patients: in total, 109 judgements on IBP were made by 13 experts in 20 patients; †ASAS validation study: in total 648 judgements on IBP in 648 patients from 25 centres worldwide were made by the local rheumatologist; ‡Calin criteria refers to IBP criteria by Calin et al,4 which are fulfilled if at least 4 of the following 5 items are present: (1) age at onset <40 years; (2) back pain >3 months; (3) insidious onset; (4) associated with morning stiffness; (5) improvement with exercise; ¶Berlin criteria refers to IBP criteria by Rudwaleit et al,6 which are fulfilled if at least 2 of the following 4 items are present: (1) morning stiffness >30 min; (2) improvement with exercise but not with rest; (3) awakening in the second half of the night because of back pain; (4) alternating buttock pain.