| Univariate analysis regression coefficient (95% CI) | p Value | Multivariate analysis regression coefficient (95% CI)* | p Value | |
| Total population | ||||
| Weight (kg) | 0.7 (0.04 to 1.4) | 0.04 | 1.0 (0.2 to 1.8) | 0.02 |
| BMI (kg/m2) | 2.7 (0.4 to 5.0) | 0.02 | 2.9 (0.6 to 5.2) | 0.01 |
| Fat mass (kg) | 1.8 (0.5 to 3.1) | 0.01 | 1.8 (0.5 to 3.1) | 0.01 |
| Percentage fat (%) | 1.4 (−0.1 to 2.8) | 0.06 | 2.0 (0.2 to 3.9) | 0.03 |
| Men only | ||||
| Weight (kg) | 1.2 (−0.2 to 2.6) | 0.09 | 1.1 (−0.3 to 2.6) | 0.13 |
| BMI (kg/m2) | 3.0 (−2.1 to 8.1) | 0.25 | 2.9 (−2.2 to 8.0) | 0.26 |
| Fat mass (kg) | 1.8 (−0.7 to 4.3) | 0.15 | 1.8 (−0.8 to 4.4) | 0.17 |
| Percentage fat (%) | 2.3 (−1.4 to 5.9) | 0.22 | 2.3 (−1.4 to 6.0) | 0.22 |
| Women only | ||||
| Weight (kg) | 1.0 (0.1 to 1.9) | 0.04 | 1.0 (−0.01 to 2.0) | 0.05 |
| BMI (kg/m2) | 2.8 (0.3 to 5.3) | 0.03 | 3.0 (0.5 to 5.6) | 0.02 |
| Fat mass (kg) | 1.7 (0.2 to 3.2) | 0.03 | 1.8 (0.2 to 3.4) | 0.03 |
| Percentage fat (%) | 1.8 (−0.3 to 3.9) | 0.09 | 1.9 (−0.2 to 4.0) | 0.08 |
*Annual loss of patella cartilage volume (mm3) per unit increase in the respective adiposity measures after adjusting for age, gender (total population only), baseline patella bone and cartilage volume, and participation in physical activity causing dyspnoea or diaphoresis (yes/no) in the regression equation. BMI, body mass index.