Table 2 Relationship between obesity and adiposity measures and the annual loss (mm3) of patella cartilage volume
Univariate analysis regression coefficient (95% CI)p ValueMultivariate analysis regression coefficient (95% CI)*p Value
Total population
    Weight (kg)0.7 (0.04 to 1.4)0.041.0 (0.2 to 1.8)0.02
    BMI (kg/m2)2.7 (0.4 to 5.0)0.022.9 (0.6 to 5.2)0.01
    Fat mass (kg)1.8 (0.5 to 3.1)0.011.8 (0.5 to 3.1)0.01
    Percentage fat (%)1.4 (−0.1 to 2.8)0.062.0 (0.2 to 3.9)0.03
Men only
    Weight (kg)1.2 (−0.2 to 2.6)0.091.1 (−0.3 to 2.6)0.13
    BMI (kg/m2)3.0 (−2.1 to 8.1)0.252.9 (−2.2 to 8.0)0.26
    Fat mass (kg)1.8 (−0.7 to 4.3)0.151.8 (−0.8 to 4.4)0.17
    Percentage fat (%)2.3 (−1.4 to 5.9)0.222.3 (−1.4 to 6.0)0.22
Women only
    Weight (kg)1.0 (0.1 to 1.9)0.041.0 (−0.01 to 2.0)0.05
    BMI (kg/m2)2.8 (0.3 to 5.3)0.033.0 (0.5 to 5.6)0.02
    Fat mass (kg)1.7 (0.2 to 3.2)0.031.8 (0.2 to 3.4)0.03
    Percentage fat (%)1.8 (−0.3 to 3.9)0.091.9 (−0.2 to 4.0)0.08
  • *Annual loss of patella cartilage volume (mm3) per unit increase in the respective adiposity measures after adjusting for age, gender (total population only), baseline patella bone and cartilage volume, and participation in physical activity causing dyspnoea or diaphoresis (yes/no) in the regression equation. BMI, body mass index.