Table 5 Change in cartilage thickness over the entire subchondral bone area (ThCtAB) over 1 year for participants with radiographic OA (ROA: K-L grade ⩾2) and frequent symptoms (FS), with ROA and obesity, with K-L grade 3 and obesity and with K-L grade 3, obesity and FS
ROA+FS (n = 87)ROA+obesity (n = 57)K-L 3+obesity (n = 29)K-L 3+obesity+FS (n = 23)
MC%SRMp ValueMC%SRMp ValueMC%SRMp ValueMC%SRMp Value
MT−0.52−0.160.04*−0.95−0.240.08*−0.81−0.170.37−0.35−0.070.74
cMF−1.92−0.30<0.001*−3.98−0.46<0.001*−4.38−0.480.02*−5.06−0.520.02*
MFTC−1.23−0.31<0.001*−2.45−0.450.001*−2.48−0.420.03*−2.55−0.400.07
LT−0.68−0.230.005*−1.11−0.390.005*−1.27−0.490.01*−1.40−0.510.02*
cLF0.090.020.770.060.010.920.460.100.610.310.060.77
LFTC−0.30−0.110.17−0.52−0.180.17−0.39−0.130.50−0.53−0.160.44
  • *p Values <0.05 for paired t test between baseline and 1 year, without correcting for multiple testing, showing that the rate of loss was significantly different from zero. For abbreviations see the footnotes of table 1.