Table 1 Characteristics of the 113 patients with Wegener granulomatosis (WG) followed in our internal medicine department
CharacteristicValue
General:
Median (range) age at WG diagnosis, years49 (13 to 79)
Male sex, n (%)67 (59)
Median (range) years of WG follow-up6 (0 to 22)
Year of WG diagnosis, median (range)1998 (1984 to 2006)
WG diagnosed before 1996, n33
WG diagnosed in/after 1996, n80
Baseline WG localisation, (%):
Ear, nose and throat93 (82)
    Rhinitis61 (54)
    Sinusitis59 (52)
    Otitis14 (12)
Eye involvement25 (22)
Lung73 (65)
    Alveolar haemorrhage20 (18)
    Nodules53 (47)
    Condensation/infiltrates19 (17)
    Pleuritis3 (3)
Glomerulonephritis62 (55)
Other organ involvement58 (51)
    Skin21 (19)
    Arthralgias39 (35)
    Digestive tract6 (5)
    Central nervous system4 (4)
    Myalgias3 (3)
    Heart3 (3)
    Pericarditis2 (2)
    Peripheral neuropathy10 (9)
    Testis1 (1)
    Hypophysis1 (1)
Ever use of any agent, (%):
CYC110 (97)
CS110 (97)
AZA58 (51)
MTX27 (24)
MMF19 (17)
Intravenous Ig18 (16)
Infliximab10 (9)
Rituximab9 (8)
Plasma exchanges8 (7)
Etanercept2 (2)
Infection-associated risk factors, (%)25 (22)
Outcome, (%):
Death8 (7)
Infection-related death2 (2)
  • AZA, azathioprine; CS, corticosteroid; CYC, cyclophosphamide; MMF, mycophenolate mofetil; MTX, methotrexate.