Table 1 Quantitative mRNA transcripts of tumour necrosis factor (TNF)α and of interleukin (IL)1β extracted 4 h after stimulation of peripheral blood mononuclear cells (PBMCs) from nine healthy donors with endotoxin from Escherichia coli with or without two different concentrations of monosodium urate (MSU) crystals

	Median (range)
	TNFα/β₂-microglobulin	IL1β/β₂-microglobulin
Medium	1.00	1.00
1 ng/ml LPS	17.83 (0.44–64.65)	5.50 (0.29–11.05)
100 μg/ml crystals	1.73 (1.21–45.36)	0.41 (0.23–6.35)
10 μg/ml crystals	2.07 (0.23–46.00)	0.14 (0.08–0.26)
1 ng/ml LPS +100 μg/ml crystals	11.36 (0.32–45.00)	4.40 (0.90–140.00)
1 ng/ml LPS +10 μg/ml crystals	39.55 (0.56–40.37)	1.40 (0.93–127.41)

Results are given as ratios with the transcripts of β₂-microglobulin.