Comparison of cardiac MRI findings between patients with and patients without precapillary pulmonary arterial hypertension (PAH)
Patients with PAH(n = 12) | Patients without PAH(n = 40) | p Value | |
Patients with at least one cardiac MRI abnormality, n (%) | 9 (75) | 30 (75) | 1.00 |
Morphological abnormalities | |||
Increased signal intensity in T2 weighted sequence, n (%) | 3 (27) | 3 (8) | 0.11 |
Thinned LV myocardium, n (%) | 4 (33) | 11 (8) | 0.72 |
LV dilatation, n (%) | 1 (8) | 2 (5) | 0.55 |
RV hypertrophy, n (%) | 2 (17) | 0 (0) | 0.04 |
RV dilatation, n (%) | 4 (33) | 7 (17) | 0.25 |
Pericardial effusion, n (%) | 5 (42) | 5 (13) | 0.04 |
Functional abnormalities | |||
LV kinetic abnormalities, n (%) | 3 (25) | 13 (32) | 0.73 |
RV kinetic abnormalities, n (%) | 2 (17) | 3 (8) | 0.32 |
Mean (SD) LV ejection fraction, % | 61 (10) | 60 (8) | 0.69 |
Impaired LV ejection fraction, n (%) | 3 (25) | 9 (23) | 1.00 |
Mean (SD) LV end-diastolic volumes, ml/m2 | 66 (18) | 69 (14) | 0.39 |
Mean (SD) cardiac output, l/min | 5.6 (1.7) | 5.0 (1.2) | 0.21 |
Mean (SD) RV ejection fraction, % | 54 (13) | 50 (11) | 0.20 |
Impaired RV ejection fraction, n (%) | 2 (17) | 9 (23) | 1.00 |
Mean (SD) RV end-diastolic volumes, ml/m2 | 75 (9) | 79 (23) | 0.67 |
LV diastolic dysfunction on transmitral flow analysis, n (%) | 5 (50) | 10 (30) | 0.49 |
Delayed contrast enhancement, n (%) | 1 (8) | 10 (26) | 0.42 |
LV, left ventricle; PAH, precapillary pulmonary arterial hypertension on right heart catheterisation; RV, right ventricle.