Comparison of cardiac MRI findings between patients with limited cutaneous SSc and patients with diffuse cutaneous SSc
| Limited cutaneous SSc(n = 32) | Diffuse cutaneous SSc(n = 20) | p Value | |
| Patients with at least one cardiac MRI abnormality, n (%) | 24 (75) | 15 (75) | 1.00 |
| Morphological abnormalities | |||
| Increased signal intensity in T2-weighted sequence, n (%) | 2 (7) | 4 (20) | 0.20 |
| Thinned LV myocardium, n (%) | 8 (25) | 7 (35) | 0.44 |
| LV dilatation, n (%) | 1 (3) | 2 (10) | 0.55 |
| RV hypertrophy, n (%) | 1 (3) | 1 (5) | 1.00 |
| RV dilatation, n (%) | 5 (16) | 6 (30) | 0.29 |
| Pericardial effusion, n (%) | 7 (22) | 3 (15) | 0.72 |
| Functional abnormalities | |||
| LV kinetic abnormalities, n (%) | 10 (31) | 6 (30) | 0.92 |
| RV kinetic abnormalities, n (%) | 3 (9) | 2 (10) | 1.00 |
| Mean (SD) LV ejection fraction, % | 59 (10) | 62 (7) | 0.20 |
| Impaired LV ejection fraction | 11 (34) | 1 (5) | 0.02 |
| Mean (SD) LV end-diastolic volumes, ml/m2 | 68 (14) | 69 (17) | 1.00 |
| Mean (SD) cardiac output, l/min | 4.8 (1.4) | 5.6 (1.3) | 0.04 |
| Mean (SD) RV ejection fraction, % | 52 (12) | 50 (10) | 0.31 |
| Impaired RV ejection fraction, n (%) | 6 (19) | 5 (25) | 0.73 |
| Mean (SD) RV end-diastolic volumes, ml/m2 | 73 (11) | 87 (28) | 0.03 |
| LV diastolic dysfunction on transmitral flow analysis, n (%) | 11/29 (38) | 4/14 (7) | 0.41 |
| Delayed contrast enhancement, n (%) | 6 (19) | 5 (25) | 0.73 |
Data are mean (SD) or absolute number (%).
LV, left ventricle; RV, right ventricle; SSc, systemic sclerosis.