| Location | Baseline mean (SD) | Mean change (SD) from model | SRM for mean change | % change (SD) | Mean change in knees with K&L = 2 or 3(SD) n = 116 | Mean change in knees with K&L = 2–4 and varus angulation (SD) n = 59 |
| Femur | 2.34 (0.37) | −0.0054 (0.058) | −0.093 | −0.23 (2.87) | −0.0082 (0.062) | −0.0034 (0.071) |
| Lat Tibia | 2.27 (0.43) | −0.017 (0.063) | −0.269 | −0.75 (4.09) | −0.019 (0.087) | −0.018 (0.090) |
| Med Tibia | 1.81 (0.38) | −0.0014 (0.079) | −0.017 | 0.14 (5.16) | 0.0086 (0.092) | −0.00088 (0.094) |
| Patella | 2.27 (0.80) | −0.018 (0.11) | −0.162 | −0.92 (7.92) | −0.024 (0.11) | −0.0060 (0.107) |
| Trochlea | 2.30 (0.55) | −0.0013 (0.073) | −0.018 | −0.20 (4.27) | −0.0066 (0.083) | 0.0092 (0.094) |
| Cent Lat Femur | 2.25 (0.41) | −0.0090 (0.071) | −0.126 | −0.39 (3.58) | −0.0094 (0.079) | −0.0095 (0.082) |
| Cent Lat Tibia | 2.36 (0.51) | −0.015 (0.071) | −0.215 | −0.66 (4.28) | −0.017 (0.093) | −0.016 (0.091) |
| Cent Med Femur | 1.88 (0.69) | −0.039 (0.12) | −0.338 | −1.92 (12.22) | −0.035 (0.11) | −0.040 (0.12) |
| Cent Med Tibia | 1.76 (0.46) | −0.0043 (0.098) | −0.044 | −0.20 (6.87) | 0.0057 (0.11) | −0.0048 (0.11) |
| Post Lat Femur | 2.61 (0.41) | 0.028 (0.13) | 0.223 | 1.15 (5.46) | 0.024 (0.14) | 0.034 (0.14) |
| Post Med Femur | 2.40 (0.43) | −0.0069 (0.090) | −0.076 | −0.01 (4.50) | −0.013 (0.10) | −0.016 (0.10) |
| Cent+Post Med Femur | 4.28 (0.98) | −0.046 (0.15) | −0.296 | −0.83 (4.32) | −0.047 (0.16) | −0.056 (0.17) |
| Cent+PostMedFemur+MedTibia | 6.09 (1.30) | −0.047 (0.19) | −0.244 | −0.57 (3.87) | −0.039 (0.21) | −0.057 (0.22) |
Cent, central; K&L, Kellgren and Lawrence (grade); Lat, lateral; Med, medial; Post, posterior; SRM, standardised response mean.