| Weight at 20 years | ||||
| Q1 | Q2 | Q3 | Q4 | |
| Median weight, kg (men/women) | 60/49 | 65/53 | 70/56 | 78/63 |
| TKR for osteoarthritis, n (per 1000 person-years) | 85 (1.1) | 51 (1.0) | 108 (1.6) | 137 (1.9) |
| RR* (95% CI) | 1.00 | 0.80 (0.55 to 1.2) | 1.3 (1.0 to 1.8) | 1.6 (1.2 to 2.1) |
| RR† (95% CI) | 1.00 | 0.78 (0.54 to 1.1) | 1.1 (0.84 to 1.5) | 1.1 (0.82 to 1.4) |
| THR for osteoarthritis, n (per 1000 person-years) | 92 (1.2) | 72 (1.4) | 123 (1.8) | 172 (2.4) |
| RR* (95% CI) | 1.00 | 1.2 (0.90 to 1.7) | 1.5 (1.1 to 1.9) | 1.9 (1.5 to 2.5) |
| RR† (95% CI) | 1.00 | 1.2 (0.88 to 1.6) | 1.4 (1.0 to 1.8) | 1.6 (1.3 to 2.1) |
*Relative risks (RR) adjusted for age, sex, smoking, physical activity. †RR adjusted for age, sex, smoking, physical activity and body mass index at baseline examination (in quartiles). Analysis based on 9341 men (141 total knee replacements (TKR) and 145 total hip replacements (THR)) and 14 667 women (240 TKR and 314 THR).