Table 3 Incidence of knee arthroplasty due to osteoarthritis during a mean follow-up of 11 years, in relation to measures of overweight
Q1Q2Q3Q4
BMI
    Median, kg/m2 (men/women)22.5/21.125.0/23.627.0/26.030.1/30.1
    Knee osteoarthritis, n (per 1000 person-years)30 (0.38)74 (0.93)131 (1.7)236 (3.1)
    Adjusted RR (95% CI)1.002.5 (1.6 to 4.0)4.6 (2.9 to 7.1)8.1 (5.3 to 12.4)
Weight
    Median, kg (men/women)69/5677/6484/7095/81
    Knee osteoarthritis, n (per 1000 person-years)41 (0.50)77 (1.0)114 (1.4)239 (3.1)
    Adjusted RR (95% CI)1.002.2 (1.4 to 3.2)3.0 (2.0 to 4.4)6.5 (4.6 to 9.3)
Waist
    Median, cm (men/women)82/6790/7496/80105/90
    Knee osteoarthritis, n (per 1000 person-years)32 (0.40)92 (1.1)115 (1.5)232 (3.0)
    Adjusted RR (95% CI)1.002.6 (1.7 to 4.1)3.6 (2.4 to 5.5)6.7 (4.5 to 9.9)
WHR
    Median (men/women)0.88/0.740.92/0.770.96/0.811.01/0.85
    Knee osteoarthritis, n (per 1000 person-years)82 (1.0)100 (1.3)124 (1.6)165 (2.2)
    Adjusted RR (95% CI)1.001.4 (1.01 to 1.9)1.6 (1.2 to 2.2)2.2 (1.7 to 3.0)
Body fat %
    Median, % (men/women)15/2519/2922/3226/37
    Knee osteoarthritis, n (per 1000 person-years)51 (0.64)84 (1.1)139 (1.6)197 (2.6)
    Adjusted RR (95% CI)1.001.8 (1.2 to 2.5)2.2 (1.6 to 3.1)3.6 (2.6 to 5.0)
Height
    Median, cm (men/women)168/157174/162178/165184/170
    Knee osteoarthritis, n (per 1000 person-years)110 (1.5)123 (1.5)133 (1.8)105 (1.3)
    Adjusted RR (95% CI)1.001.2 (0.9 to 1.5)1.5 (1.2 to 2.0)1.1 (0.8 to 1.5)
  • Each quartile consists of approximately 2756 men and 4233 women. Relative risks (RR) adjusted for age, sex, smoking, physical activity (in quartiles). BMI, body mass index; WHR, waist/hip ratio.