Q1 | Q2 | Q3 | Q4 | |
BMI | ||||
Median, kg/m2 (men/women) | 22.5/21.1 | 25.0/23.6 | 27.0/26.0 | 30.1/30.1 |
Knee osteoarthritis, n (per 1000 person-years) | 30 (0.38) | 74 (0.93) | 131 (1.7) | 236 (3.1) |
Adjusted RR (95% CI) | 1.00 | 2.5 (1.6 to 4.0) | 4.6 (2.9 to 7.1) | 8.1 (5.3 to 12.4) |
Weight | ||||
Median, kg (men/women) | 69/56 | 77/64 | 84/70 | 95/81 |
Knee osteoarthritis, n (per 1000 person-years) | 41 (0.50) | 77 (1.0) | 114 (1.4) | 239 (3.1) |
Adjusted RR (95% CI) | 1.00 | 2.2 (1.4 to 3.2) | 3.0 (2.0 to 4.4) | 6.5 (4.6 to 9.3) |
Waist | ||||
Median, cm (men/women) | 82/67 | 90/74 | 96/80 | 105/90 |
Knee osteoarthritis, n (per 1000 person-years) | 32 (0.40) | 92 (1.1) | 115 (1.5) | 232 (3.0) |
Adjusted RR (95% CI) | 1.00 | 2.6 (1.7 to 4.1) | 3.6 (2.4 to 5.5) | 6.7 (4.5 to 9.9) |
WHR | ||||
Median (men/women) | 0.88/0.74 | 0.92/0.77 | 0.96/0.81 | 1.01/0.85 |
Knee osteoarthritis, n (per 1000 person-years) | 82 (1.0) | 100 (1.3) | 124 (1.6) | 165 (2.2) |
Adjusted RR (95% CI) | 1.00 | 1.4 (1.01 to 1.9) | 1.6 (1.2 to 2.2) | 2.2 (1.7 to 3.0) |
Body fat % | ||||
Median, % (men/women) | 15/25 | 19/29 | 22/32 | 26/37 |
Knee osteoarthritis, n (per 1000 person-years) | 51 (0.64) | 84 (1.1) | 139 (1.6) | 197 (2.6) |
Adjusted RR (95% CI) | 1.00 | 1.8 (1.2 to 2.5) | 2.2 (1.6 to 3.1) | 3.6 (2.6 to 5.0) |
Height | ||||
Median, cm (men/women) | 168/157 | 174/162 | 178/165 | 184/170 |
Knee osteoarthritis, n (per 1000 person-years) | 110 (1.5) | 123 (1.5) | 133 (1.8) | 105 (1.3) |
Adjusted RR (95% CI) | 1.00 | 1.2 (0.9 to 1.5) | 1.5 (1.2 to 2.0) | 1.1 (0.8 to 1.5) |
Each quartile consists of approximately 2756 men and 4233 women. Relative risks (RR) adjusted for age, sex, smoking, physical activity (in quartiles). BMI, body mass index; WHR, waist/hip ratio.