SAE of interest, events/100 patient-years, as of 15 April 2007
| Rheumatoid arthritis | Psoriatic arthritis | Ankylosing spondylitis | Juvenile idiopathic arthritis | Psoriasis | Crohn’s disease | |
| N | 12 345 | 837 | 1641 | 171 | 1819 | 2228 |
| Exposure (patient-years) | 18 284.3 | 997.5 | 1255.2 | 398.4 | 2424.7 | 2373.7 |
| Serious infections | 4.65 | 2.81 | 1.11 | 2.76 | 1.32 | 5.18 |
| Tuberculosis | 0.29 | 0.30 | 0 | 0 | 0.12 | 0.13 |
| Opportunistic infections | 0.09 | 0 | 0 | 0 | 0 | 0.08 |
| Histoplasmosis | 0.03 | 0 | 0 | 0 | 0 | 0 |
| Malignancies excluding lymphoma and NMSC | 0.76 | 0.30 | 0.08 | 0 | 0.49 | 0.46 |
| Lymphoma | 0.12 | 0.20 | 0.08 | 0 | 0 | 0.08 |
| NMSC | 0.17 | 0 | 0.08 | 0 | 0.12 | 0 |
| Demyelinating disorder | 0.05 | 0 | 0.08 | 0 | 0 | 0.13 |
| Lupus-like syndrome | 0.07 | 0 | 0 | 0 | 0 | 0.04 |
| Congestive heart failure | 0.23 | 0 | 0.16 | 0 | 0 | 0 |
NMSC, non-melanoma skin cancer; SAE, serious adverse event.