Table 3 Digital x ray radiogrammetry bone mineral density (DXR-BMD) as a predictor for subsequent increase in vdH Sharp score in patients with rheumatoid arthritis (RA) at 5-year and 10-year follow-up in multivariate logistic regression models

	Logistic regression analyses
	Increase ⩾5 units at 5 years		Increase ⩾10 units at 10 years
	β	Odds ratio (95% CI)	β	Odds ratio (95% CI)
DXR-BMD loss>LSC at 1 year	1.26	3.52 (1.42 to 8.75)	1.24	3.46 (1.43 to 8.35)
Baseline vdH Sharp score ⩾1	1.60	4.94 (2.01 to 12.10)	1.45	4.27 (1.78 to 10.27)
Positive anti-CCP	1.44	4.20 (1.77 to 9.98)	1.28	3.59 (1.54 to 8.38)
Elevated CRP (cut-off 10)	0.98	2.66 (0.92 to 7.72)	0.45	1.57 (0.59 to 4.19)
Age	−0.02	0.98 (0.94 to 1.02)	−0.01	0.99 (0.95 to 1.03)
Female gender	0.34	1.41 (0.52 to 3.86)	0.84	2.32 (0.88 to 6.10)
Constant	−1.61		−2.11
Goodness of fit (Nagelkerke R square)	0.44		0.39

CCP, cyclic citrullinated peptide; CRP, C-reactive protein; vdH Sharp, van der Heijde modification of the Sharp score.