Table 3 Digital x ray radiogrammetry bone mineral density (DXR-BMD) as a predictor for subsequent increase in vdH Sharp score in patients with rheumatoid arthritis (RA) at 5-year and 10-year follow-up in multivariate logistic regression models
Logistic regression analyses
Increase ⩾5 units at 5 yearsIncrease ⩾10 units at 10 years
βOdds ratio (95% CI)βOdds ratio (95% CI)
DXR-BMD loss>LSC at 1 year1.263.52 (1.42 to 8.75)1.243.46 (1.43 to 8.35)
Baseline vdH Sharp score ⩾11.604.94 (2.01 to 12.10)1.454.27 (1.78 to 10.27)
Positive anti-CCP1.444.20 (1.77 to 9.98)1.283.59 (1.54 to 8.38)
Elevated CRP (cut-off 10)0.982.66 (0.92 to 7.72)0.451.57 (0.59 to 4.19)
Age−0.020.98 (0.94 to 1.02)−0.010.99 (0.95 to 1.03)
Female gender0.341.41 (0.52 to 3.86)0.842.32 (0.88 to 6.10)
Constant−1.61−2.11
Goodness of fit (Nagelkerke R square)0.440.39
  • CCP, cyclic citrullinated peptide; CRP, C-reactive protein; vdH Sharp, van der Heijde modification of the Sharp score.