Table 1

Baseline characteristics of the three AS cohorts (totalling 692 patients) in whom the original BASDAI was compared with the mini-BASDAI

Baseline parameters(1) GESPIC cohort*(2) TNFα trial population†(3) NSAID trial population‡
No of patients (N)22891373
% Male64.9%69.2%69.2%
% HLA-B27-positive83.8%88.9%NA
Mean age, in years (SD)35.4 (10.2)37.8 (8.4)43.9 (12.4)
Mean disease duration, in years (SD)5.3 (2.7)14.2 (8.3)NA
BASDAI (0–10), mean (SD)3.94 (2.10)6.51 (1.23)4.66 (1.60)
Mini-BASDAI (0–10), mean (SD)4.72 (2.12)7.00 (1.24)5.54 (1.64)
BASFI (0–10), mean (SD)3.20 (2.50)5.42 (2.01)4.27 (2.22)
Patient global (0–10), mean (SD)5.04 (2.55)7.25 (1.75)6.23 (1.76)
% of patients without peripheral manifestation (“P−” group)§70.6%39.6%100%‡
  • *German Spondyloarthritis Inception Cohort (GESPIC), 228 ankylosing spondylitis (AS) patients seen cross-sectionally at baseline in 13 centres in Germany.22

  • †Tumour necrosis factor alpha (TNFα) trial population, 91 patients who were treated with infliximab or etanercept in the setting of clinical trials.23 24

  • ‡Non-steroidal anti-inflammatory drug (NSAID) trial population, 373 AS patients who were treated with either celecoxib (200 mg a day or 200 mg twice a day) or diclofenac 75 mg twice a day for 12 weeks in the setting of a double-blind, randomised controlled trial in 46 German study centres. Peripheral arthritis was an exclusion criterion.25

  • §“P−”, subgroup of patients without peripheral involvement.

  • BASDAI, Bath Ankylosing Spondylitis Disease Activity Index; mini-BASDAI, BASDAI without Q3arthritis and Q4enthesitis; BASFI, Bath Ankylosing Spondylitis Functional Index; NA, not assessed.