Adverse events (AE) reported for steroid injections versus placebo or other comparator
Adverse event | No (%) of AE in patients treated with corticoids* | Comparator | No (%) of AE patients treated with comparator* | NNH |
All | 121/713 (16.97) | Placebo | 34/566 (6.01) | 9 |
Physiotherapy | 80/203 (39.41) | −4 | ||
NSAID | 11/181 (6.08) | 9 | ||
Pain | 76/713 (10.66) | Placebo | 19/566 (3.36) | 14 |
Physiotherapy | 54/203 (26.60) | −6 | ||
NSAID | 0/181 (0) | 9 | ||
Skin atrophy and depigmentation | 29/713 (4.07) | Placebo | 5/566 (0.88) | 31 |
Physiotherapy | 6/203 (2.96) | 90 | ||
NSAID | 0/181 (0) | 25 | ||
Gastrointestinal upset | 1/713 (0.14) | Placebo | 1/566 (0.18) | −2500 |
Physiotherapy | 0/203 (0) | 714 | ||
NSAID | 7/181 (3.87) | −27 | ||
Facial flush | 3/713 (4.21) | Placebo | 0/566 (0) | 24 |
Physiotherapy | 0/203 (0) | 24 | ||
NSAID | 0/181 (0) | 24 |
*In studies where the AE was reported.
NNH, number needed to harm; NSAID, non-steroidal anti-inflammatory drug.