Table 1 Variables determining the subdivision into different groups
GroupPhenotypeGround glass on HRCTFibrosis chest x rayVC p%DLCO p%Serum COMP patients, nmRssUS performed
Limited cross-sectionallcSScNo>80>701
Diffuse cross-sectionaldcSScNo>80>701
Alveolitis cross-sectionalYes1
Fibrosis cross-sectionaldcSScYes<80<701
Low-longitudinal3–5Never > 10
High-longitudinal3–5Once 25
US cross-sectional1Yes
  • COMP, cartilage oligomeric matrix protein; dcSSc, diffuse cutaneous systemic sclerosis; DLCO, diffusing capacity for carbon monoxide; HRCT, high-resolution computed tomography; lcSSc, limited cutaneous systemic sclerosis; mRss, modified Rodnan skin score; p%, percentage of predicted value; US, ultrasound; VC, vital capacity.