Adalimumab | Etanercept | Infliximab | |
DAS28 | |||
Baseline | 5.3 (1.3) | 5.5 (1.2) | 5.2 (1.3) |
3 months: | |||
Decrease | −1.6 (1.3)* | −1.5 (1.2)* | −0.9 (1.5) |
EULAR response (%) | 76%* | 74%* | 57% |
6 months: | |||
Decrease | −1.8 (1.4)* | −1.6 (1.3)* | −1.1 (1.4) |
EULAR response (%) | 78%* | 75%* | 57% |
9 months: | |||
Decrease | −1.8 (1.4)* | −1.9 (1.4)* | −1.1 (1.3) |
EULAR response (%) | 79%* | 79%* | 62% |
12 months: | |||
Decrease | −1.8 (1.5)* | −1.8 (1.4)* | −1.2 (1.4) |
EULAR response (%) | 78%* | 80%* | 61% |
HAQ | |||
Baseline | 1.3 (0.7) | 1.4 (0.7) | 1.4 (0.7) |
3 months: | |||
Decrease | −0.35 (0.5)* | −0.33 (0.5)* | −0.19 (0.5) |
6 months: | |||
Decrease | −0.42 (0.5)* | −0.35 (0.5) | −0.23 (0.5) |
9 months: | |||
Decrease | −0.40 (0.5)* | −0.36 (0.6) | −0.26 (0.5) |
12 months: | |||
Decrease | −0.42 (0.6)* | −0.35 (0.6) | −0.26 (0.5) |
Values are means with standard deviations between brackets unless stated otherwise. Missing values at baseline, 3, 6, 9, 12 months, respectively: DAS28, 5.1%, 4.0%, 10.6%, 12.6%, 15.1%; HAQ, 9.9%, 9.2%, 12.2%, 15.6%, 16.3%
*Significant difference (<0.05) compared to infliximab patients.