Dependent variable | Test model effects | ||||
Independent variable | B estimate | 95% Wald CI | |||
Lower | Upper | p Value | |||
DAS28 3v-CRP | Intercept | 2.637 | 1.575 | 3.699 | 0.000 |
Rheumatoid factor | −0.71 | −1.063 | −0.357 | 0.000 | |
Sex | 0.705 | −0.021 | 1.431 | 0.057 | |
Visits at week 6 | −0.899 | −1.24 | −0.56 | 0.000 | |
Visits at week 30 | −0.85 | −1.16 | −0.54 | 0.000 | |
FCGR3A (FV-VV vs FF genotypes) | 0.226 | −0.306 | 0.758 | 0.405 | |
FCGR2A (HR-HH vs RR genotypes) | 0.206 | −0.354 | 0.766 | 0.471 | |
Interactions: | |||||
Interaction between FCGR3A and visits | 0.019 | ||||
Interaction between FCGR2A and visits | 0.082 | ||||
A posteriori contrasting Bonferroni test: | Mean differences | ||||
At baseline: differences in DAS28 between FV-VV and FF groups | 0.107 | −0.370 | 0.584 | 0.661 | |
At 6 weeks: differences in DAS28 between FV-VV and FF groups | 0.753 | 0.305 | 12.002 | 0.001 | |
At 30 weeks: differences in DAS28 between FV-VV and FF groups | −0.226 | −0.758 | 0.306 | 0.405 |
CRP, C-reactive protein; DAS28, 28-joint Disease Activity Score.