MRI spine (n = 46) | MRI sacroiliac joints (n = 42) | MRI spine and sacroiliac joints (n = 26) | |
Demographic and clinical parameters: | |||
Age (years)* | 38.1 (9.0) | 37.9 (9.0) | 38.1 (9.6) |
Disease duration (years) | 14.6 (8.8) | 14.5 (8.9) | 13.9 (9.2) |
Male sex (%) | 65.2 | 59.5 | 57.7 |
HLA-B27 positive (%) | 89.1 | 87.8 | 84.6 |
BASDAI at baseline | 6.5 (1.2) | 6.5 (1.3) | 6.6 (1.4) |
BASFI at baseline | 5.5 (2.1) | 5.1 (2.1) | 5.4 (2.2) |
BASMI at baseline | 3.7 (2.1) | 3.6 (2.0) | 3.8 (2.0) |
CRP at baseline | 24.4 (23.7) | 23.1 (18.6) | 22.5 (17.5) |
Patients (%) with: | |||
CRP >6 mg/litre† | 73.9 | 71.4 | 73.1 |
CRP >25 mg/litre | 37.0 | 38.1 | 38.5 |
MRI: | |||
Berlin MRI spine score: | |||
Total spine (range) | 5.2 (6.1) (0–23) | – | 4.7 (6.3) (0–23) |
Cervical spine (range) | 0.5 (1.4) (0–6) | – | 0.4 (1.3) (0–6) |
Thoracic spine (range) | 3.8 (4.5) (0–16) | – | 3.5 (4.7) (0–14) |
Lumbar spine (range) | 0.9 (1.3) (0–4) | – | 0.8 (1.2) (0–4) |
MRI SI joints score (range) | – | 2.3 (2.6) (0–10) | 2.2 (2.4) (0–8) |
Patients (%) with MRI spine score ⩾1 | 73.9 | – | 65.4 |
Patients (%) with MRI SI joint score ⩾1 | – | 61.9 | 65.4 |
Clinical response | |||
ASAS 20 response (%) | 73.9 | 73.8 | 73.1 |
ASAS 40 response (%) | 56.5 | 61.9 | 57.7 |
ASAS 5/6 response (%) | 58.7 | 66.7 | 61.5 |
BASDAI 50 response (%) | 54.3 | 61.9 | 57.7 |
In total, MRIs were available from 62 patients. Of these, 46 patients had MRIs of the spine and 42 patients had MRIs of the SI joints; in 26 of the 62 patients MRIs of spine and SI joints were available.
*Mean (SD) values are given if not indicated otherwise. †Normal range for CRP is ⩽6 mg/litre.
ASAS, Assessments of Spondyloarthritis; BASDAI, Bath Ankylosing Spondylitis Disease Activity Index; BASFI, Bath Ankylosing Spondylitis Functional Index; BASMI, Bath Ankylosing Spondylitis Metrology Index; CRP, C-reactive protein; HLA, human leukocyte antigen.